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: SNAP8

SNAP-8 is a cosmetic peptide for reducing facial wrinkles. Relaxes muscle activity, smoothes the skin and helps to maintain natural facial expressions without the effect of "freezing".

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SNAP-8 Description:

SNAP-8 is a new generation cosmetic peptide with a targeted effect on facial wrinkles. It is often referred to as a mild alternative to injection methods, as it reduces excessive muscle activity without disrupting natural facial expressions. The peptide works at the level of neuromuscular transmission, helping to relax skin areas prone to crease formation. As a result, the skin looks smoother, rested and visually younger, without the effect of a "frozen" face. SNAP-8 is widely used in premium anti-aging skin care formulas, especially in the forehead, eye, and nasolabial areas. It fits well into long-term anti-age programs aimed at preventing and correcting age-related changes. SNAP is an 8-point work with facial expressions when naturalness, comfort and a neat aesthetic result are important.

General information

Features Values
The peptide sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
The molecular formula  C42H72N16O15S
Molecular weight 1073.2 g/mol
CAS Number  868844-74-0
PubChem CID 71587832
Synonyms SNAP-8, Acetyl Octapeptide-3, Acetyl Glutamyl Heptapeptide-3

Lyophilized peptides
All peptides undergo lyophilization, a process that is necessary to extend their shelf life, as well as preserve the purity and integrity of the peptides during storage and transportation. Product Usage: This product is intended solely for research purposes. All product information provided on this website is intended for educational purposes.

Product Usage
This product is intended solely for research purposes. All product information provided on this website is intended for educational purposes.

The purity of peptides is more than 99%
Confirmed by certified laboratories. The analysis certificates are available before purchase.

GMR Production Standards
Manufactured in enterprises in accordance with good manufacturing practices. Complete documentation on tracking the origin of the product.

Execution of orders at the highest level
Sending orders the next day at checkout before 12:00 Moscow time. Free standard shipping across the country for orders starting from 15,000₽ (or equivalent).

Without fillers and additives
Only pure active connections. The composition is confirmed by experts for reliable in vitro studies.

SNAP-8 is a cosmetic neuropeptide, more correctly known as acetyl octapeptide-3. It belongs to topical anti-age peptides and is studied primarily in the context of facial wrinkles, reduction of tension lines, and mild neuromodulation at the skin level. In reviews on cosmetic peptides, SNAP-8 is described as a peptide based on the Argireline mechanism, with an emphasis on suppressing the processes associated with the formation of the SNARE complex and the release of a neurotransmitter signal, which explains its interest as an ingredient for anti-wrinkle products. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy - PMC

Anti-aging effect
The main research area of SNAP-8 is related to reducing the severity of facial wrinkles, especially in areas of active facial expression, such as the forehead and periorbital region. The 2024 review of non-invasive peptide alternatives to botulinum therapy provides clinical evidence of a marked reduction in wrinkle depth, up to 38% over 28 days of use in cosmetic formulas, although such results usually relate to specific ready-made compositions rather than an isolated molecule outside the formula. 

Mechanism of action
SNAP-8 is usually classified as a peptide with a neurotransmitter-inhibiting profile. In scientific reviews, its mechanism is described as mimicry of the SNAP-25 region with a competitive effect on the formation of the SNARE complex, which can reduce the intensity of the signal associated with muscle contraction, and thereby mitigate the formation of facial lines. It is important to correctly present this as a cosmetic neuromodulation, and not as a complete replacement for botulinum toxin. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy - PMC

Cosmetic application
For the website, SNAP-8 is better described as a peptide for research and development of anti-age cosmetics focused on dynamic wrinkles and skin texture. Lubrizol's official technical materials for SNAP-8 peptide solution C explicitly refer it to anti-wrinkle ingredients and recommend its use in cosmetic formulas for external use, rather than as a systemic peptide. SNAP-8 peptide solution C - Lubrizol

Comparison with Argireline
SNAP-8 is often positioned as a longer and improved analogue of acetyl hexapeptide-8, i.e. Argireline. In reviews of cosmetic peptides, it is presented as the next generation of neuropeptides for the correction of facial wrinkles, but it is important not to overstate this comparison, because most of these claims are based on cosmetic and formulary data, rather than large independent clinical head-to-head studies. Anti-aging peptides for advanced skincare: Focus on nanodelivery systems - ScienceDirect

Links

  1. Peptides: Emerging Candidates for the Prevention and Treatment of Skin Aging. 2025. Peptides: Emerging Candidates for the Prevention and Treatment of Skin Senescence: A Review - PMC
  2. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. 2020. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy - PMC
  3. Anti-aging peptides for advanced skincare. 2023. Anti-aging peptides for advanced skincare: Focus on nanodelivery systems - ScienceDirect
  4. Non-Invasive Peptides as the Future of Botox Alternatives. 2024.
  5. Method development for acetyl octapeptide-3 analysis by LC-MS/MS. 2020. Development of methods for the analysis of acetyloctapetide-3 using liquid chromatography and tandem mass spectrometry | Journal of Analytical Science and Technology | Springer Nature Link
  6. Lubrizol. SNAP-8 peptide solution C technical page. SNAP-8 peptide solution C - Lubrizol
  7. SpecialChem. INCI entry for Acetyl Octapeptide-3. ACETYL OCTAPEPTIDE3