MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial peptide discovered in 2015 that functions as a mitochondrial regulatory signal. This 16-amino acid peptide is encoded by the 12S rRNA gene in the mitochondrial genome and represents a crucial link between mitochondrial function and metabolism. MOTS-c primarily affects skeletal muscle and acts as a metabolic regulator by activating the AMPK (AMP-activated protein kinase) pathway, which is critical for cellular energy homeostasis.

General Information

Properties	Values
Sequence Peptide	Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Molecular formula	C101H152N28O22S2
Molecular weight	2174.6 g/mol
CAS number	1627580-64-6
PubChem CID	146675088
Synonyms	MOTS-c (human) (trifluoroacetate salt), A5CV6JFB78

Product Usage
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